| Computer-Aided Drug Discovery Contributor(s): Zhang, Wei (Editor) |
|
 |
ISBN: 1493935194 ISBN-13: 9781493935192 Publisher: Humana OUR PRICE: $151.99 Product Type: Hardcover - Other Formats Published: June 2016 |
| Additional Information |
| BISAC Categories: - Medical | Pharmacology |
| Dewey: 615 |
| LCCN: 2016942864 |
| Series: Methods in Pharmacology and Toxicology |
| Physical Information: 0.75" H x 7" W x 10" (1.70 lbs) 305 pages |
| Descriptions, Reviews, Etc. |
| Publisher Description: This detailed volume examines computer-aided drug discovery (CADD), a crucial component of modern drug discovery programs that is widely utilized to identity and optimize bioactive compounds for the development of new drugs. With a focus on the methods that are commonly used in the early stage of drug discovery, chapters explore computer simulation, structure prediction, conformational sampling, binding site mapping, docking and scoring, in silico screening, and fragment-based drug design. In addition to the state-of-the-art theoretical concept, this book also includes step-by-step, readily reproducible computational protocols as well as examples of various CADD strategies. The limitations and potential pitfalls of different computational methods are discussed by experts, and tips and advice for their applications are suggested. |