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Growth Hormone Secretagogues in Clinical Practice
Contributor(s): Bercu, Barry B. (Author), Walker, Richard F. (Author)
ISBN: 0367400480     ISBN-13: 9780367400484
Publisher: CRC Press
OUR PRICE:   $75.95  
Product Type: Paperback - Other Formats
Published: September 2019
Qty:
Temporarily out of stock - Will ship within 2 to 5 weeks
Additional Information
BISAC Categories:
- Medical | Endocrinology & Metabolism
- Medical | Pediatrics
- Medical | Genetics
Dewey: 615.363
Physical Information: 504 pages
 
Descriptions, Reviews, Etc.
Publisher Description:

Recognizing the urgent need for an up-to-date review of new and innovative research on growth hormone (GH) secretagogues, this exclusive work furnishes the state of the art on the mechanisms of action, design, synthesis, evaluation, and clinical applications of GH secretagogues, including orally active and xenobiotic GH-releasing compounds.
Beginning with a thorough historical perspective on the discovery and evolution of GH-releasing peptides (GHRPs) as therapeutic agents, Growth Hormone Secretagogues in Clinical Practice

  • analyzes structural requirements for GH secretagogue efficacy
  • demonstrates the use of mathematical models to predict differential values of individual stimuli for GH secretion from the pituitary
  • reports on the development of a simple screening system based on polyclonal antibodies
  • discusses laboratory synthesis of agonistic analogs intended for human and veterinary use
  • proposes applications in managing conditions such as Turner's syndrome, acromegaly, diabetic retinopathy, glomerulosclerosis, tumors, and cancer
  • provides physiological evidence for the effects of GHRP on behavior with a series of trials involving voluntary and forced exercise
  • describes a new diagnostic test for evaluating pituitary function in slowly growing children and aging adults
  • explores the interactions of GH secretagogues with other hormones and endogenous substances from sex steroids to interferons
  • and much more!
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