| Aging Methods and Protocols 2000 Edition Contributor(s): Barnett, Yvonne A. (Editor), Barnett, Christopher R. (Editor) |
|
 |
ISBN: 0896035824 ISBN-13: 9780896035829 Publisher: Humana OUR PRICE: $104.49 Product Type: Hardcover - Other Formats Published: May 2000 Annotation: Yvonne and Christopher Barnett and a team of recognized international experts detail key biochemical, analytical, and molecular techniques for the investigation of aging at the cellular, tissue, organ, and whole system levels. These cutting-edge methods address a wide range of research needs, from uncovering the factors associated with cell senescence and death, to exploring alterations in the body's ability both to metabolize xenobiotics and to defend itself against biomolecular damage. State-of-the-art protocols also measure the morphological, functional, and molecular changes that accumulate within mitochrondria over time, and permit the genetic and functional characteristics of the immune system to be determined. Wide ranging and highly practical, Aging Methods and Protocols provides today's molecular gerontologists, pharmacologists, and clinical investigators with a gold-standard collection of readily reproducible techniques for identifying those key cellular and molecular processes that might one day make it possible to regulate the aging process. |
| Additional Information |
| BISAC Categories: - Medical | Biochemistry - Science | Life Sciences - Molecular Biology - Science | Life Sciences - Developmental Biology |
| Dewey: 571.878 |
| LCCN: 99023842 |
| Series: Methods in Molecular Medicine |
| Physical Information: 1.17" H x 6.3" W x 9.28" (1.70 lbs) 385 pages |
| Descriptions, Reviews, Etc. |
| Publisher Description: Aging is an almost universal process within biological systems, one which leads to a decline in functional capacity, disease onset, and eventually death. There has been much interest in recent years to elucidate the molecular mec- nisms that underlie the aging process. Many theories have been proposed since the last century that aim to explain the causes of aging. There is no one theory that completely satisfies the phenotype of aging, but genetics and environm- tal factors play an important role in the etiology of age-related pathologies and the aging process. However, there is still much to be learned about the aging process which has been termed one of the last great frontiers in biology. De- graphic changes worldwide are leading to increased average life expectancies within our populations. These changes in population characteristics will impact upon the economies of the supporting society, with increasing healthcare and infrastructural costs arising from the prevalence of age-related pathologies and other physical disabilities associated with advancing years. Many researchers worldwide are working in the attempt to identify key cellular processes through which it might one day be possible to slow down the aging process and thus increase the health span of humans. Numerous research projects--from the cellular through to tissue, organ, and whole organism studies--are currently underway to investigate the mul- factorial aging process. |