| Angiotensin Protocols 2001 Edition Contributor(s): Wang, Donna H. (Editor) |
|
 |
ISBN: 0896037630 ISBN-13: 9780896037632 Publisher: Humana OUR PRICE: $161.49 Product Type: Hardcover - Other Formats Published: October 2000 Annotation: Donna Wang and a panel of hands-on experts describe in step-by-step detail all the major molecular, biochemical, and functional techniques now used in probing the renin-angiotensin system. These range from the use of embryonic gene targeting to create of mutant strains, to the functional investigation of components of the renin-angiotensin system. Comprehensive and highly practical, Angiotensin Protocols translates expert knowledge into readily reproducible methods that enable all biomedical investigators successfully to explore the role of angiotensin in health and disease today. |
| Additional Information |
| BISAC Categories: - Medical | Biochemistry - Medical | Genetics - Medical | Physiology |
| Dewey: 612.015 |
| LCCN: 00027598 |
| Series: Methods in Molecular Medicine |
| Physical Information: 1.28" H x 6.28" W x 9.34" (2.29 lbs) 530 pages |
| Descriptions, Reviews, Etc. |
| Publisher Description: A qualitative leap in the understanding of cardiovascular and n- ral regulation by the renin-angiotensin system, and of the role of this s- tem in tissue damage, has occurred as a result of the many recent advances in molecular genetic techniques. The cloning of the genes for the components of the renin-angiotensin system, the design of specific angiotensin receptor ligands, and the use of embryonic gene targeting te- niques for the creation of mutant strains have established that the renin- angiotensin system is important in blood pressure regulation, ion and fluid homeostasis, and tissue growth and remodeling Further investigation of the mechanisms by which this system p- ticipates in cardiovascular regulation may shed some light on the pat- genesis of several cardiovascular diseases, e. g., hypertension, congestive heart failure, and chronic renal failure. Despite the promise of this system as a target for therapeutic interventions for these diseases, there are great challenges in the integration of the attempts to close the gap between the traditional literature of medicine and the explosion of information from the new technologies. This book's title, Angiotensin Protocols, reflects the authors' strong efforts to translate expert knowledge into easy-to-follow practice. The book opens with introductory chapters, and each specialty section provides detailed methods covering a wide variety of techniques, ranging from genetic manipulation of targeted genes to functional studies of the renin- angiotensin system. |