Cellular and Molecular Toxicology and In Vitro Toxicology Contributor(s): Acosta, Daniel (Author) |
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ISBN: 1138557811 ISBN-13: 9781138557819 Publisher: CRC Press OUR PRICE: $46.48 Product Type: Paperback - Other Formats Published: January 2019 |
Additional Information |
BISAC Categories: - Medical | Toxicology |
Series: CRC Press Revivals |
Physical Information: 0.38" H x 6" W x 9" (0.54 lbs) 176 pages |
Descriptions, Reviews, Etc. |
Publisher Description: This work concentrates on cellular and molecular toxicity of selected well-known drugs or chemicals on the cardiovascular system. The primary objective is to provide a better understanding of the mechanisms by which xenobiotics are toxic to mammalian tissues and cells. The use of in vitro cellular and tissue systems provides attractive experimental models to assess toxic manifestations of xenobiotics. This work addresses the most recent findings on the cellular and molecular mechanisms of toxicity of several important cardiotoxic agents: doxorubicin, ethanol, cocaine, and the catecholamines. It presents an overview of vascular toxins and their biochemical effects. Included is a summary of in vitro cardiovascular techniques for assessing toxicity of xenobiotics. This publication is important for those in toxicology, tissue culture, pharmacology, in vitro toxicology, developmental biology and related areas. |