| Pharmacogenetics of Breast Cancer: Towards the Individualization of Therapy Contributor(s): Leyland-Jones, Brian (Editor) |
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ISBN: 1420052934 ISBN-13: 9781420052930 Publisher: CRC Press OUR PRICE: $199.50 Product Type: Hardcover - Other Formats Published: May 2008 Annotation: Pharmacogenetics, generally referred to as the study of genetic variation that gives rise to differing response to drugs, is becoming more relevant in the diagnosis, treatment, and recovery of cancer patients. The problem faced when treating cancer is the outstanding varied efficacy between success and failure. Unpredictability between a population of patients who are affected with the same occurring malignancy can show varying associated toxicities in drug treatment ranging from zero effect through lethal doses. Since the chemotherapeutic agent is often developed to fit the average patient the unfortunate result is that approximately 40% of patients may be receiving the wrong drug. However, using pharmacogenetics there are promising advancements in the development of effective agents which will enable 'personalized cancer chemotherapy' to become routine for the clinical practice. This individualization is most advanced in the field of breast cancer; while many breast oncologists are individualizing techniques based on specific profiles, within 10 years it is likely all breast oncologists will be using RT-PCR, FISH-based multiplexed arrays, or a similar testing regime for patient individualization therapy. |
| Additional Information |
| BISAC Categories: - Medical | Oncology - Breast Cancer - Medical | Genetics - Medical | Gynecology & Obstetrics |
| Dewey: 616.994 |
| LCCN: 2008001013 |
| Series: Translational Medicine |
| Physical Information: 0.85" H x 6.27" W x 9.04" (1.33 lbs) 350 pages |
| Descriptions, Reviews, Etc. |
| Publisher Description: Pharmacogenetics is becoming increasingly relevant in the diagnosis, treatment, and recovery of cancer patients. A major problem facing oncologists is the outstanding varied efficacy of treatment. Promising advances in pharmacogenetics have allowed the development of effective agents which will enable personalized cancer chemotherapy to become routine for the clinical practice. Written by experts in the field and combining information that is unable to be found in a single source volume, Pharmacogenetics of Breast Cancer:
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