| A Dissertation Report on Tuberculosis Immunology Contributor(s): Sharma, Gaurav (Author), Beenu Joshi (Author) |
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ISBN: 3639343859 ISBN-13: 9783639343854 Publisher: VDM Verlag OUR PRICE: $50.27 Product Type: Paperback Published: March 2011 |
| Additional Information |
| BISAC Categories: - Science | Life Sciences - Biochemistry |
| Physical Information: 0.25" H x 6" W x 9" (0.36 lbs) 104 pages |
| Descriptions, Reviews, Etc. |
| Publisher Description: Tuberculosis (TB) is the major cause of death worldwide. The enormity of the problem has been further worsened by the emergence of multi-drug resistant (MDR) strains and the dual infection with HIV. A newly identified TB threat which leaves patients virtually untreatable using currently available anti-TB drugs is XDR-TB. Protein extracted from whole cell lysate (WCL) during late log growth phase often considered candidate components for diagnosis of Tuberculosis and vaccine.In any cell proteins are ultimately working moiety, therefore proteomic analysis and seroreactivity in relation to identify a molecule could be much informative. This study includes the analysis and comparison of whole cell lysate proteins of two clinical isolates with M. tuberculosis H37Rv strain and their reactivity for searching a immunodominant antigen. Present study suggest that current clinical isolate of M. tuberculosis might be valuable to characteristics some unique dominant targets for tuberculosis diagnosis and for vaccine candidate. |