| Additional Information |
| BISAC Categories: - Science | Life Sciences - Biochemistry - Medical | Neuroscience |
| Series: RSC Drug Discovery |
| Physical Information: 0.87" H x 6.32" W x 9.34" (1.25 lbs) 270 pages |
| Descriptions, Reviews, Etc. |
| Publisher Description: Since Alois Alzheimer described the results of his postmortem studies in 1906, significant strides have been made in understanding the pathogenesis of neurodegenerative diseases. The latest advances suggest that deficiencies in protein homeostasis, or proteostasis, may lead to cell dysfunction and disease. This book updates the new key developments in this fast moving field. The traditional views concerning the relationship between the physio-pathological cycles of Copper, Zinc, Iron, Aluminium and the evolution of life, are compared with the new emerging ideas in the neuroscience of metal ions. Topics covered emphasize the importance of metals and oxydation chemistry to neuroscientists as well as providing a wider, multidisciplinary background to chemists who are attracted by these fascinating subjects. |